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Fragrance safety experts, scientists and industry leaders from around the world gathered at Le Méridien Etoile for a one-day event.
November 3, 2025
By: Melissa Meisel
On Sept. 29, 2025, fragrance safety experts, scientists and industry leaders from around the world gathered at Le Méridien Etoile in Paris for RIFM INFOX 2025, an immersive, full-day event dedicated to advancing fragrance safety through innovation, science, and collaboration.
Hosted by the Research Institute for Fragrance Materials (RIFM), this year’s program highlighted how decades of rigorous research and forward-looking methodologies continue to define global fragrance safety science. The day featured a dynamic lineup of presentations from RIFM scientists and members of the Expert Panel for Fragrance Safety, alongside interactive discussions that reinforced the importance of transparency, collaboration, and continual evolution in the field.
RIFM President Anne Marie Api, PhD, Fellow ATS, opened the event by welcoming attendees and reflecting on the Institute’s enduring mission.
“Fragrance safety is well-established, yet the science continues to evolve, enhancing confidence as tools, data, and understanding advance,” Dr. Api said. “What makes RIFM unique is how we integrate innovation with collaboration to ensure that every fragrance ingredient is assessed using the most current, comprehensive science available.”
The morning sessions focused on RIFM’s leadership in next-generation risk assessment, the power of data-driven exposure modeling, and new frontiers in environmental safety. Danielle Botelho, PhD, RIFM’s Director of Scientific Operations, illustrated how the Institute’s scientific framework has adapted to incorporate New Approach Methodologies (NAMs) and robust evaluation tools for both individual fragrance ingredients and complex natural substances.
In one of the day’s highlights, RIFM Principal Scientist Gretchen Ritacco, MS, presented the Creme RIFM Aggregate Exposure Model, showcasing how RIFM’s state-of-the-art system provides realistic exposure data that strengthen confidence in safety outcomes.
RIFM Principal Scientist Aurelia Lapczynski unveiled the next evolution of RIFM’s Environmental Framework 2.0, emphasizing ecological relevance and sustainability in fragrance safety evaluations, while Christen Sachse Vasquez, Executive Director, Technical Information & Services, traced the enduring impact of the RIFM Database, a cornerstone of evidence-based fragrance science for more than half a century.
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